全文获取类型
收费全文 | 2809331篇 |
免费 | 205419篇 |
国内免费 | 11710篇 |
专业分类
耳鼻咽喉 | 37911篇 |
儿科学 | 90162篇 |
妇产科学 | 77882篇 |
基础医学 | 394251篇 |
口腔科学 | 77289篇 |
临床医学 | 254693篇 |
内科学 | 556433篇 |
皮肤病学 | 67534篇 |
神经病学 | 228897篇 |
特种医学 | 108230篇 |
外国民族医学 | 812篇 |
外科学 | 422505篇 |
综合类 | 61568篇 |
现状与发展 | 15篇 |
一般理论 | 1020篇 |
预防医学 | 206298篇 |
眼科学 | 63391篇 |
药学 | 208411篇 |
39篇 | |
中国医学 | 8168篇 |
肿瘤学 | 160951篇 |
出版年
2019年 | 23240篇 |
2018年 | 32956篇 |
2017年 | 25465篇 |
2016年 | 29126篇 |
2015年 | 33163篇 |
2014年 | 45449篇 |
2013年 | 66145篇 |
2012年 | 88045篇 |
2011年 | 92731篇 |
2010年 | 56061篇 |
2009年 | 53610篇 |
2008年 | 85860篇 |
2007年 | 91340篇 |
2006年 | 92713篇 |
2005年 | 88617篇 |
2004年 | 84658篇 |
2003年 | 81610篇 |
2002年 | 78523篇 |
2001年 | 142971篇 |
2000年 | 146046篇 |
1999年 | 122651篇 |
1998年 | 33166篇 |
1997年 | 29064篇 |
1996年 | 28707篇 |
1995年 | 29409篇 |
1994年 | 26898篇 |
1993年 | 24973篇 |
1992年 | 93851篇 |
1991年 | 89824篇 |
1990年 | 86634篇 |
1989年 | 83793篇 |
1988年 | 76632篇 |
1987年 | 74836篇 |
1986年 | 69930篇 |
1985年 | 66444篇 |
1984年 | 48969篇 |
1983年 | 41296篇 |
1982年 | 24041篇 |
1981年 | 21321篇 |
1979年 | 42387篇 |
1978年 | 29500篇 |
1977年 | 25117篇 |
1976年 | 22929篇 |
1975年 | 24558篇 |
1974年 | 28822篇 |
1973年 | 27311篇 |
1972年 | 25715篇 |
1971年 | 23921篇 |
1970年 | 21981篇 |
1969年 | 21204篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
991.
N. Tanaka Y. Kunihiro R. Kawano T. Yujiri K. Ueda T. Gondo T. Matsumoto 《Clinical radiology》2021,76(1):50-59
992.
993.
994.
L. Martínez Santos U. Olabarrieta Zarain A. García Trancho R.M. Serna de la Rosa I. Vallinas Hidalgo M.J. Maroño Boedo A. Martínez Ruiz 《Revista espa?ola de anestesiología y reanimación》2021,68(1):46-49
Pregnant women experience physiological and immunological changes which make them more prone to all kind of viral and bacterial infections, this is because they have been considered as vulnerable group if infected by SARS-CoV-2. They could even deploy a severe form of this disease which may require to end pregnancy to improve oxygenation and to safeguard foetal wellbeing the in case the mother situation gets worse. In this scenario, any intervention would require a detailed planning by the whole surgical team, and, specifically, by the anaesthesiologists, in order to guarantee both mother and child wellbeing and to prevent from infections all the healthcare team. We describe the case of 37 week pregnant woman, admitted in our Critical Care Unit with respiratory high flows device support, due to severe respiratory failure due to COVID-19 which needed an urgent caesarean section. 相似文献
995.
996.
997.
998.
Emad A. Rakha Islam M. Miligy Cecily M. Quinn Elena Provenzano Abeer M. Shaaban Caterina Marchi Michael S. Toss Grace Gallagy Ciara Murray Janice Walshe Ayaka Katayama Karim Eldib Nahla Badr Bruce Tanchel Rebecca Millican-Slater Colin Purdie Dave Purnell Sarah E. Pinder Ian O. Ellis Andrew H. S. Lee 《British journal of cancer》2021,124(11):1836
Background The ASCO/CAP guidance on HER2 testing in breast cancer (BC) has recently changed. Group 2 tumours with immunohistochemistry score 2+ and HER2/CEP17 ratio ≥2.0 and HER2 copy number <4.0 signals/cell were re-classified as HER2 negative. This study aims to examine the response of Group 2 tumours to neoadjuvant chemotherapy (NACT).Methods 749 BC cases were identified from 11 institutions. The association between HER2 groups and pathological complete response (pCR) was assessed.Results 54% of immunohistochemistry HER2 positive (score 3+) BCs showed pCR, compared to 19% of immunohistochemistry 2+ FISH amplified cases. 27% of Group 2 treated with HER2 targeted therapy achieved pCR, compared to 19 and 11% in the combined Groups 1 + 3 and Groups 4 + 5, respectively. No difference in pCR rates was identified between Group 2 and Group 1 or combined Groups 1 + 3. However, Group 2 response rate was higher than Groups 4 + 5 (p = 0.017).Conclusion No difference in pCR was detected in tumours with a HER2/CEP17 ratio ≥2.0 and a HER2 score 2+ by IHC when stratified by HER2 gene copy number. Our data suggest that ASCO/CAP HER2 Group 2 carcinomas should be evaluated further with respect to eligibility for HER2 targeted therapy.Subject terms: Breast cancer, Breast cancer 相似文献
999.
1000.
Arafat S. M. Yasir Kar Sujita Kumar Kabir Russell 《International journal of mental health and addiction》2021,19(6):2289-2291
International Journal of Mental Health and Addiction - 相似文献